田野,女,博士,副研究员,中国科学院青年创新促进会会员。2006年7月于北京化工大学高分子材料与工程专业获工学学士学位,2011年7月于中国科学院化学研究所高分子物理与化学专业获理学博士学位,2011-2012年在加拿大曼尼托巴大学从事博士后研究,于2012年11月加入中国科学院理化技术研究所工作。近年来主要从事生物纳米粒子的功能化、自组装及生物医学应用的研究工作,作为项目负责人主持国家自然科学基金、北京市自然科学基金、中国科学院、北京市教委、企业横向等科研项目近10项。在Proc. Natl. Acad. Sci. U. S. A.、J. Am. Chem. Soc.、Nano Lett.等期刊发表学术论文40余篇,参编国际专著1部,获授权发明专利2项。
1.生物医用高分子材料
2.生物纳米粒子的功能化、自组装及应用
3.大分子抗菌材料
1.国家自然科学基金“基于多功能化生物纳米粒子/血小板复合体的RNA干扰系统用于纤维化抑制研究”;
2.国家自然科学基金“基于规整蛋白组装体的靶向抗肿瘤药物载体的研究”;
3.北京市自然科学基金面上项目“氟尾/细胞穿膜肽双修饰蛋白的自组装及构建仿病毒基因载体”;
4.中国科学院青年创新促进会人才项目。
1. Xiaoyan Ju#, Jun Chen#, Mengxue Zhou, Meng Zhu, Zhuang Li, Sijia Gao, Jinzhao Ou, Dandan Xu, Man Wu, Shidong Jiang, Yi Hu, Ye Tian*, Zhongwei Niu*, Combating Pseudomonas aeruginosa Biofilms by a Chitosan-PEG-Peptide Conjugate via Changes in Assembled Structure, ACS Appl. Mater. Interfaces 2020, 12, 13731-13738.
2. Sijia Gao, Zhuang Li, Zhicheng Sun, Jinyue Wen, Furong Li, Xiaoyang Du, Yan Liu, Ye Tian*, Zhongwei Niu*, Single-Wavelength Excited Ratiometric Fluorescence pH Probe to Image Intracellular Trafficking of Tobacco Mosaic Virus, Chinese J. Polym. Sci. 2020, 38, 587-592.
3. Sijia Gao#, Xuzhou Yan#,*, Guocheng Xie, Meng Zhu, Xiaoyan Ju, Peter J. Stang*, Ye Tian*, Zhongwei Niu, Membrane Intercalation-Enhanced Photodynamic Inactivation of Bacteria by a Metallacycle and TAT-Decorated Virus Coat Protein, Proc. Natl. Acad. Sci. U. S. A. 2019, 116, 23437-23443.
4. Xiaoxue Ren, Shidong Jiang, Man Wu, Haigang Shi, Ye Tian*, Zhongwei Niu*, Phenotype Regulation of Smooth Muscle Cells Through Facial Crystallization of Poly(?-Caprolactone), J. Nanosci. Nanotechnol. 2019, 19, 2269-2275.
5. Ye Tian, Mengxue Zhou, Haigang Shi, Sijia Gao, Guocheng Xie, Meng Zhu, Man Wu, Jun Chen, Zhongwei Niu*, Integration of Cell-Penetrating Peptides with Rod-like Bionanoparticles: Virus-Inspired Gene-Silencing Technology, Nano Lett. 2018, 18, 5453-5460.
6. Sijia Gao, Xiangxiang Liu, Zhaocheng Wang, Shidong Jiang, Man Wu, Ye Tian*, Zhongwei Niu*, Fluorous Interaction Induced Self-Assembly of Tobacco Mosaic Virus Coat Protein for Cisplatin Delivery, Nanoscale 2018, 10, 11732-11736.
7. Zhaocheng Wang, Sijia Gao, Xiangxiang Liu, Ye Tian*, Man Wu, Zhongwei Niu*, Programming Self-Assembly of Tobacco Mosaic Virus Coat Proteins at Pickering Emulsion Interfaces for Nanorod-Constructed Capsules, ACS Appl. Mater. Interfaces 2017, 9, 27383-27389.
8. Xiangxiang Liu, Bowei Liu, Sijia Gao, Zhaocheng Wang, Ye Tian*, Man Wu, Shidong Jiang, Zhongwei Niu*, Glyco-decorated Tobacco Mosaic Virus as a Vector for Cisplatin Delivery, J. Mater. Chem. B 2017, 5, 2078-2085. (Front Cover)
9. Quan Zhou, Xiangxiang Liu, Ye Tian*, Man Wu, Zhongwei Niu*, Mussel-Inspired Polydopamine Coating on Tobacco Mosaic Virus: One-Dimensional Hybrid Nanofibers for Gold Nanoparticle Growth, Langmuir 2017, 33, 9866-9872.
10. Ye Tian#, Xuzhou Yan#, Manik Lal Saha, Zhongwei Niu*, Peter J. Stang*, Hierarchical Self-Assembly of Responsive Organoplatinum(II) Metallacycle-TMV Complexes with Turn-On Fluorescence, J. Am. Chem. Soc. 2016, 138, 12033-12036.
11. Ye Tian, Sijia Gao, Man Wu, Xiangxiang Liu, Jing Qiao, Quan Zhou, Shidong Jiang, Zhongwei Niu*, Tobacco Mosaic Virus-Based 1D Nanorod-Drug Carrier via the Integrin-Mediated Endocytosis Pathway, ACS Appl. Mater. Interfaces 2016, 8, 10800-10807.
12. Ye Tian, Man Wu, Xiangxiang Liu, Zhi Liu, Quan Zhou, Zhongwei Niu*, Yong Huang, Probing the Endocytic Pathways of the Filamentous Bacteriophage in Live Cells Using Ratiometric pH Fluorescent Indicator, Adv. Healthcare Mater. 2015, 4, 413-419. (Frontispiece)
13. Ye Tian, Yi Kong, Xiaojian Li, Jun Wu, Alex C.-T. Ko, Malcolm Xing*, Light- and pH-Activated Intracellular Drug Release from Polymeric Mesoporous Silica Nanoparticles, Colloids and Surfaces B: Biointerfaces 2015, 134, 147-155.
14. Ye Tian, Aleksandra Glogowska, Wen Zhong, Thomas Klonisch*, Malcolm Xing*, Polymeric Mesoporous Silica Nanoparticles as a pH-Responsive Switch to Control Doxorubicin Intracellular Delivery, J. Mater. Chem B 2013, 1, 5264-5272.
15. Ye Tian, Jian Chen, Fatemeh Zahtabi, Richard Keijzer*, Malcolm Xing*, Nanomedicine as an Innovative Therapeutic Strategy for Pediatric Lung Diseases, Pediatr. Pulmonol. 2013, 48, 1098-1111.
16. Ye Tian, Min Wu*, Xiaobo Lin, Pei Huang, Yong Huang*, Synthesis of Magnetic Wheat Straw for Arsenic Adsorption, J. Hazard. Mater. 2011, 193, 10-16.
17. Ye Tian, Min Wu*, Ruigang Liu, Deqian Wang, Xiaobo Lin, Weili Liu, Lin Ma, Yanding Li, Yong Huang*, Modified Native Cellulose Fibers - A Novel Efficient Adsorbent for both Fluoride and Arsenic, J. Hazard. Mater. 2011, 185, 93-100.
18. Ye Tian, Min Wu*, Ruigang Liu, Yanxiang Li, Deqian Wang, Junjun Tan, Rongcheng Wu, Yong Huang*, Electrospun Membrane of Cellulose Acetate for Heavy Metal Ion Adsorption in Water Treatment, Carbohydr. Polym. 2011, 83, 743-748.
2016年入选中国科学院青年创新促进会
人才队伍