• 姓名: 王雪松
  • 性别: 男
  • 职称: 研究员
  • 职务: 所长
  • 学历: 理学博士
  • 电话: 010-82543761
  • 传真: 
  • 电子邮件: xswang@mail.ipc.ac.cn
  • 通讯地址: 北京海淀区中关村东路29号
    简  历:
  • 1986.08-1991.07,中国科学技术大学,高分子化学,理学学士;

    1991.08-1996.07,中科院感光化学研究所,有机化学,理学博士;

    1996.08-1998.06,中科院感光化学研究所,历任助研、副研;

    1998.06-2000.06,美国夏威夷大学,博士后;

    2000.06-2023.06,中科院理化技术研究所,历任研究员、博士生导师、课题组长、业务处长、副所长。

    2023.07-至今,中科院理化技术研究所,所长。


    社会任职:
  • 中国化学会光化学专业委员会副主任
    研究方向:
  • 长期从事有机光化学、光物理领域的基础和应用开发研究:

    1)光疗药物:研究光敏药物同生物大分子相互作用机制,发展对肿瘤细胞和致病菌具有高效光杀伤能力的新型光敏药物;

    2)光化学合成:研究光反应的机理及放量技术,利用光化学反应制备药物及药物中间体,探索光化学反应绿色化学化工领域的应用。
    承担科研项目情况:
  • 1.科技部973计划,重大疾病相关的若干重要难检活性小分子细胞内纳米传感研究

    2.科技部863计划,重污染化工行业清洁生产技术与示范

    3.国家自然科学基金重大项目,“C-H键活化和高效转化的基本科学问题

    4.中科院战略性先导科技专项(B类),能源化学转化的本质与调控:高效太阳能光化学转化

    5.中科院知识创新工程重要方向项目:光化学绿色合成新技术—16-DPA光敏氧化合成法;

    6.国家自然科学基金委面上项目十余项
    代表论著:
  • 1.       Qianxiong Zhou, Wanhua Lei, Yongjie Chen, Chao Li, Yuanjun Hou, Baowen Zhang, Xuesong Wang*, Ruthenium(II)-Arene Complexes with Strong Fluorescence: Insight into the Underlying Mechanism, Chem. Eur. J. 2012, 18, 8617-8621.

    2.       Jingfan Xie, Qianxiong Zhou, Chao Li, Weibo Wang, Yuanjun Hou*, Baowen ZhangXuesong Wang*An unexpected role of the monodentate ligand in photocatalytic hydrogen production of the pentadentate ligand-based cobalt complexesChem. Commun. 2014, 506520-6522.

    3.Yue Zheng, Qianxiong Zhou*,Wanhua Lei, Yuanjun Hou, Ke Li, Yongjie Chen, Baowen Zhang, Xuesong Wang*, DNA photocleavage in anaerobic conditions by a Ru(II) complex: a new mechanism,Chem. Commun.,2015,51, 428-430.

    4.Ke Li, Yangyang Zhang, Guoyu Jiang, Yuanjun Hou, Baowen Zhang, Qianxiong Zhou*, Xuesong Wang*, A bivalent cationic dye enabling selective photoinactivation against Gram-negative bacteria,Chem. Commun., 2015, 51, 7923-7926.

    5.Qianxiong Zhou*, Yue Zheng, Tianji Wang, Yongjie Chen, Ke Li, Yangyang Zhang, Chao Li, Yuanjun Hou, Xuesong Wang*, A novel azopyridine-based Ru(II) complex with GSH-responsive DNA photobinding ability, Chem. Commun., 2015, 51, 10684-10686.

    6.       Na Tian, Weize Sun, Xusheng Guo, Jian Lu, Chao Li, Yuanjun Hou, Xuesong Wang*, Qianxiong Zhou*, Mitochondria targeted and NADH triggered photodynamic activity of chloromethyl modified Ru(II) complexes under hypoxic conditions, Chem. Commun., 2019, 55, 2676-2679.

    7.       Yang Feng, Weize Sun, Xuesong Wang*, Qianxiong Zhou*, Selective photoinactivation of methicillin-resistant staphylococcus aureus by highly positively charged Ru(II) complexes, Chem. Eur. J., 2019, 25, 13879-13884.

    8.       Na Tian, Weize Sun, Yang Feng, Xusheng Guo, Jian Lu, Chao Li, Yuanjun Hou, Xuesong Wang*, Qianxiong Zhou*, Chloromethyl-modified Ru(II) complexes enabling large pH jumps at low concentrations through photoinduced hydrolysis, Chem. Sci., 2019, 10, 9949-9953.

    9.       Youchao Wang, Nana Tian, Chao Li, Yuanjun Hou, Xuesong Wang*, Qianxiong Zhou*Incorporation of 7-dehydrocholesterol into liposomes as a simple, universal and efficient way to enhance anticancer activity by combining PDT and photoactivated chemotherapy, Chem. Commun., 2019, 55, 14081-14084.

    10.     Zhihui Jin, Shuang Qi, Xusheng Guo, Na Tian, Yuanjun Hou, Chao Li, Xuesong Wang*Qianxiong Zhou*, Smart use of “ping-pong” energy transfer to improve the two-photon photodynamic activity of an Ir(III) complex, Chem. Commun., 2020, 56, 2845-2848.

    获奖及荣誉: